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Read our, Medically reviewed by Richard N. Fogoros, MD, Medically reviewed by Yasmine S. Ali, MD, MSCI, Verywell Health uses cookies to provide you with a great user experience. Triglycerides. Mendes P, Robles PG, Mathur S. Statin-induced rhabdomyolysis: a comprehensive review of case reports. Other statins include fluvastatin, pravastatin, rosuvastatin, and simvastatin. The standard starting dose for adults is 10 to 20 mg. Those who require at least a 45% reduction in LDL cholesterol may be begin with a 40-mg dose.. Highlights of prescribing information: Lipitor. 4  Your physician may slowly increase the dose as needed based upon your LDL levels and your response to the medication. If you are taking any of these drugs with Lipitor, your healthcare provider may need to adjust your dose, monitor you more closely for side effects, or discontinue one of the drugs:. Physiother Can. These can lower LDL, the “bad” cholesterol, by up to 15%. An overview, Everything you need to know about coming off statins, Statins increase the risk of developing diabetes in at-risk people, How does high cholesterol cause cancer? In this article learn about the vegan diet, the Mediterranean diet, and the TLC diet. 2015;29(4):277-91. doi:10.1007/s40263-015-0239-x, Davies JT, Delfino SF, Feinberg CE, et al. J Pharm Health Care Sci. Lipitor may give rise to a number of side effects. By using Verywell Health, you accept our, Cholesterol & Triglycerides: What You Need to Know, An Overview of Drug-Induced Liver Disease, How Zocor (Simvastatin) Works to Lower Your Cholesterol, An Ace Inhibitor Used for Hypertension and Heart Failure, General Information About Livalo (Pitavastatin), Crestor: Uses, Side Effects, Dosages, Interactions, Metoprolol: Used to Treat High Blood Pressure and Angina, What to Know Before Starting a Bile Acid Resin to Lower LDL, How the Atrogin-1 Gene May Cause Muscle Pain for Statin Users, Taking Statins? Check your prescription and talk to your doctor to make sure you are taking the right dose for you. ... the average LDL had fallen to 77 mg/dL compared with 101 mg/dl in the low-dose Lipitor … It can also raise high-density lipoprotein (HDL, considered "good" cholesterol). People also know it as atorvastatin. If a person has dyslipidemia, or hyperlipidemia, they have a high level of cholesterol, triglycerides, or both, in the blood. If you take too much Lipitor or overdose, seek immediate medical care. What are the side effects of Lipitor? Lipitor is approved for adults and children age 10 and up. Lipitor is a statin. It is also not suitable for use while breastfeeding, as it is not clear whether the drug can enter the breast milk. If you have a history of heart attacks or you're at a very high risk of a heart attack or stroke, you may need to aim even lower (below 70 mg/dL, or 1.8 mmol/L). People with CVD are at risk of angina and myocardial infarction, or a heart attack. Statin capsules include Lescol (fluvastatin) and Ezallor (rosuvastatin), and there is an oral suspension option called FloLipid (simvastatin). Research has found that rosuvastatin reduces LDL cholesterol by an average of 51% followed by atorvastatin at 45%, simvastatin at 37%, and pravastatin at 25%.. She saw a program on the TV about it. Extended-release tablets are available as Lescol XL (fluvastatin) and Altoprev (lovastatin). The first person to synthesize Lipitor was Bruce Roth, in 1985. Lipitor can be taken with or without food. As with all drugs and all statins, Lipitor comes with the risk of side effects. Statins lower cholesterol levels in the blood by blocking 3-hydroxy-3methylglutaryl coenzyme A (HMG CoA) reductase, an enzyme that's needed for the liver to produce cholesterol. High: 160 mg/dL or higher. According to the CDC, in 2011–2012, nearly 28 percent of adults aged 40 years and over were using some kind of prescription drug to lower cholesterol. Thank you, {{form.email}}, for signing up. While you are taking Lipitor, your doctor will have you come in periodically for blood tests to monitor your cholesterol levels and to check if your dosage needs to be adjusted. Good: 149 mg/dL or lower… Alan Carter, PharmD Answers represent the opinions of our medical experts. That's because, in addition to lowering lipids (fats), Lipitor and other statins appear to have some novel effects such as influencing immune responses, enhancing anti-inflammatory processes, and altering additional signaling pathways that aren't yet fully understood. 2016;9:13-29. doi:10.4137/LPI.S37450. It is quickly absorbed, reaching its peak concentration in the blood within about two hours. Lipitor starts to lower cholesterol within about two weeks of starting the medication. Due to this link, statins such as Lipitor are also commonly prescribed to reduce the risk of heart attack, stroke, and angina in people with heart disease or those who have multiple risk factors for developing heart disease.. 2013;9(9):605-6. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. If you experience any signs of allergic reaction, seek urgent medical attention. © 2004-2020 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. For example, it may be used for people with primary hyperlipidemia (high lipid levels due to genetic factors) or mixed dyslipidemia (both triglycerides and cholesterol levels are high). Some can be serious or require treatment, so it's important to be aware of them. U.S. Food and Drug Administration. Patients who use Lipitor should not consume more than 1–2 small glasses of grapefruit juice in a day, because this can affect how the drug works. Statins reduce the levels of bad cholesterol, and this helps to prevent coronary artery disease and serious complications of CVD, such as angina, stroke, and heart attack. There are multiple types of statins and Lipitor is one of the more potent options. Cholesterol can deposit around the eyes and form fatty, yellow lumps. Regardless if you take a statin or not, lifestyle changes are necessary to reduce the risk of heart disease. What is the best time to take statins and why? If you have any of the following conditions, your healthcare provider may decide to start you on a lower dose of Lipitor and will need to monitor you to determine whether or not taking Lipitor will be potentially harmful to you: Lipitor may also need to be temporarily withheld or discontinued with certain conditions that can lead to myopathy or kidney failure with rhabdomyolysis. CNS Drugs. Statins stop the body from producing bad cholesterol by suppressing an enzyme in the liver, called HMG-CoA reductase. All rights reserved. Researchers have discovered a cell mechanism in which cholesterol influences the proliferation of stem cells and the growth of intestinal tumors in…. However, are these fears unfounded? Lipitor (atorvastatin) is a cholesterol-lowering medication that belongs to the statin class of drugs. These affect the circulation outside the heart and the brain. Lipitor comes in oral tablets and is available as a generic. Do not take two doses at once. Aim to keep this "bad" cholesterol under 100 mg/dL, or 2.6 mmol/L. Lipitor is effective at lowering cholesterol; however, its use may be limited by side … In these cases, your healthcare provider may place you on a different treatment to lower your lipids: Talk to your doctor about all medications, supplements, and vitamins that you currently take. Store the tablets at a controlled room temperature that's ideally 68 to 77 degrees F. If you miss a dose of Lipitor, take it as soon as you remember. 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